AKTIVITAS MINYAK IKAN NILA MERAH (Oreochromis niloticus) TERHADAP PENURUNAN KADAR KOLESTEROL TOTAL SERUM DARAH PADA TIKUS PUTIH JANTAN GALUR WISTAR

Aziz, Asrizal (2016) AKTIVITAS MINYAK IKAN NILA MERAH (Oreochromis niloticus) TERHADAP PENURUNAN KADAR KOLESTEROL TOTAL SERUM DARAH PADA TIKUS PUTIH JANTAN GALUR WISTAR. Skripsi thesis, Universitas Setia Budi Surakarta.

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Abstract

Hyperlipidemia is a disorder of lipid metabolism characterized by elevated levels of total cholesterol, triglycerides, LDL, and HDL decrease in blood serum that will lead to atherosclerosis. Tilapia (Oreochromis niloticus) is a type of freshwater fish that contains a variety of fatty acids that can lower total cholesterol. This study aims to determine the effect of tilapia fish oil to the decrease in total cholesterol levels in male rats and the effective dose. Oil tilapia made with dry rendering method, the separation of fish oil that are tied to water use Na2SO4anhidrat. This research was conducted in test animals 30 male rats were divided into six groups. Group I (normal control), group II (negative control PGA 0.5%), Group III (positive control simvastatin), Group IV (oil tilapia 0.8 ml / 200g BB), group V (oil tilapia 1, 6 ml / 200g BB), group IV (tilapia fish oil 3.2 ml / 200g BB). The data obtained were analyzed by One-Way ANOVA using the Shapiro-Wilk test. The results showed a decrease in total cholesterol levels at all three dose variation tilapia fish oil on the 21st day. A dose of 3.2 ml / 200g BB according to statistical data had the effect of decreasing cholesterol levels were quite high. Keywords: Oil tilapia, total cholesterol levels and male mice.

Item Type: Thesis (Skripsi)
Uncontrolled Keywords: Oil tilapia, total cholesterol levels and male mice.
Subjects: Q Science > QL Zoology
R Medicine > RS Pharmacy and materia medica
Divisions: Fakultas Farmasi > Prodi S1 Farmasi
Depositing User: magdalena kartika ningsih
Date Deposited: 23 Feb 2019 02:59
Last Modified: 23 Feb 2019 02:59
URI: http://repository.setiabudi.ac.id/id/eprint/633

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