ANALISIS EFEK PENGGUNAAN RAMIPRIL DAN CANDESARTAN PADA PASIEN RAWAT INAP PENDERITA COVID-19 DENGAN KOMORBID HIPERTENSI DI RSUD dr. MOEWARDI TAHUN 2020

Azizah, Deva Yolanda Dwi Nur (2022) ANALISIS EFEK PENGGUNAAN RAMIPRIL DAN CANDESARTAN PADA PASIEN RAWAT INAP PENDERITA COVID-19 DENGAN KOMORBID HIPERTENSI DI RSUD dr. MOEWARDI TAHUN 2020. Skripsi thesis, Universitas Setia Budi.

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Abstract

Hypertension is the most common comorbid in patients infected by COVID- 19. Drugs that are often given for the treatment of hypertension, namely ramipril and candesartan, are thought to increase the development of COVID-19 because the angiotensin converting enzyme inhibitors (ACEI) and angiotensin receptor blockers (ARBs) increase the expression of ACE-2, which is the binding site of SARS-CoV-2. This study aims to analyze the effect of using ramipril and candesartan on healing in hospitalized patients with COVID-19 with hypertension at RSUD dr. Moewardi in 2020. This study was conducted retrospectively. The results were presented descriptively, and used medical record data of hospitalized patients with COVID- 19 with comorbid hypertension at RSUD dr. Moewardi in 2020. The effect of using ramipril and candesartan on patient recovery in terms of length of stay (LOS), symptom relief, and RT-PCR test results. Analysis of the research data using SPSS with Spearman correlation test. The Spearman correlation test showed that there was a fairly strong relationship between the use of ramipril and candesartan in patients with COVID- 19 with comorbid hypertension on LOS, symptom relief, and RT-PCR test results. From the results of the study, it can be concluded that the use of ramipril and candesartan can improve the recovery of patients COVID-19 with comorbid hypertension. The use of ACEI and ARB drugs has not been proven to worsen the patient's condition so that their use can be continued. Key words: COVID-19, hypertension, hypertension in COVID-19, ramipril, candesartan

Item Type: Thesis (Skripsi)
Uncontrolled Keywords: COVID-19, hypertension, hypertension in COVID-19, ramipril, candesartan
Subjects: R Medicine > R Medicine (General)
Divisions: Fakultas Farmasi > Prodi S1 Farmasi
Depositing User: Tifany Nur Arfiana
Date Deposited: 29 Sep 2022 04:38
Last Modified: 29 Sep 2022 04:38
URI: http://repository.setiabudi.ac.id/id/eprint/5272

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