FORMULASI DAN UJI DAYA HAMBAT OBAT KUMUR EKSTRAK DAUN TEH HIJAU (Camellia sinensis L.) TERHADAP AKTIVITAS BAKTERI Streptococcus mutans ATCC 25175 SECARA in vitro

Farisca, Ayu (2019) FORMULASI DAN UJI DAYA HAMBAT OBAT KUMUR EKSTRAK DAUN TEH HIJAU (Camellia sinensis L.) TERHADAP AKTIVITAS BAKTERI Streptococcus mutans ATCC 25175 SECARA in vitro. Skripsi thesis, Universitas Setia Budi.

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Abstract

Dental caries caused by the overgrowth of Streptococcus mutans bacteria. One of prevention action to control dental caries is by using anti-bacterial mouthwash. Green tea leaves (Camellia sinensis L.) contain catechins and flavonoids that can prevent bacteria growth. This research aims to know the potention of green tea leaves extract mouthwash as anti-bacterial against Streptococcus mutans bacteria. The method used in this research is maceration method with 70% ethanol solvent. Green tea leaves extract with vary concentrations such as 1%, 2%, 3%, and 4% are made in the form of mouthwash preparations with sorbitol, tween 80, glicerol, methyl paraben, propyl paraben, and oleum menthae as constituent materials. The mouthwash is tested by Physical quality test (organoleptic, pH, viscosity) and stability test. Anti-bacteria activity tested by using diffusion method with discs. Four green tea extract formulas created good results on physical quality test and stability test, then were statisticaly analyzed by using Independent T-Test. Diffusion test results of 1%, 2%, 3%, and 4% mouthwash concentrations by measuring clear zones using caliper obtained 12,92 mm, 14,83 mm, 17,25 mm, and 18,67 mm inhibition areas. Diffusion test results of green tea extract mouthwash were statisticaly analyzed by using one way anova. Green tea extract mouthwash with 3% concentration can actively kills Streptococcus mutans bacteria ATCC 25175. Key word : Dental caries, green tea leaves (Camellia sinensis L.), Streptococcus mutans, diffusion.

Item Type: Thesis (Skripsi)
Uncontrolled Keywords: Dental caries, green tea leaves (Camellia sinensis L.), Streptococcus mutans, diffusion.
Subjects: R Medicine > RS Pharmacy and materia medica
Divisions: Fakultas Farmasi > Prodi S1 Farmasi
Depositing User: Tifany Nur Arfiana
Date Deposited: 01 Nov 2019 03:46
Last Modified: 01 Nov 2019 03:46
URI: http://repository.setiabudi.ac.id/id/eprint/3564

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