UJI AKTIVITAS ANTIJAMUR EKSTRAK ETANOLIK KULIT BATANG KAYU MANIS (Cinnamomum burmanni, Bl.), KAYU SECANG (Caesalpinia sappan, L.), dan KOMBINASINYA terhadap Candida albicans ATCC 10231

Nurfadhila, Reza (2019) UJI AKTIVITAS ANTIJAMUR EKSTRAK ETANOLIK KULIT BATANG KAYU MANIS (Cinnamomum burmanni, Bl.), KAYU SECANG (Caesalpinia sappan, L.), dan KOMBINASINYA terhadap Candida albicans ATCC 10231. Skripsi thesis, Universitas Setia Budi.

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Abstract

Cinnamon Bark (Cinnamomum burmanni, Bl.) and Sappanwood (Caesalpinia sappan, L.) is one of the traditional herbs which are efficacious as an antifungal. Cinnamon Bark contains antifungal compounds of essential oils, alkaloids, flavonoids, tannins, and saponins. Sappanwood contains alkaloid antifungal compounds, flavonoids, tannins, and saponins. This study aims to determine the antifungal activity of ethanolic extract of Cinnamon Bark, Sappanwood, and its combinations 1:1, 1: 3, 3: 1 against Candida albicans ATCC 10231, and to determine whether or not there is a synergistic effect of a combination of ethanolic extract on Candida albicans ATCC 10231. The research method used is an experimental laboratory. The extraction method for the test material using maserati. The antifungal activity test method against Candida albicans ATCC 10231 using diffusion was carried out with three repetitions. The diffusion method was carried out to determine the inhibition of Candida albicans ATCC 10231 with a concentration of 50% and 25%. Statistical analysis with ANOVA (Two Way ANOVA) test. The results showed that the extract of Cinnamon Bark, Sappanwood, and its combination had antifungal activity. Ethanolic extract of Sappanwood is the most active extract as an antifungal with inhibitory diameters at concentrations of 50% and 25%, respectively 14.3 mm and 10.7 mm. The combination of ethanolic extract 1:1, 1: 3, 3: 1 does not have a synergistic effect on Candida albicans ATCC 10231. Keywords: Cinnamon (Cinnamomum burmanni, Bl.), Sappanwood (Caesalpinia sappan, L.), antifungal, diffusion, Candida albicans ATCC 10231

Item Type: Thesis (Skripsi)
Uncontrolled Keywords: Cinnamon (Cinnamomum burmanni, Bl.), Sappanwood (Caesalpinia sappan, L.), antifungal, diffusion, Candida albicans ATCC 10231
Subjects: R Medicine > RS Pharmacy and materia medica
Divisions: Fakultas Ilmu Kesehatan > Prodi D4 Analis Kesehatan
Depositing User: Tifany Nur Arfiana
Date Deposited: 11 Oct 2019 02:50
Last Modified: 11 Oct 2019 02:50
URI: http://repository.setiabudi.ac.id/id/eprint/3360

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