UJI AKTIVITAS DIURETIK DARI MASERASI EKSTRAK ETANOL 70% DAUN PUTRI MALU (Mimosa pudica L.) TERHADAP TIKUS PUTIH JANTAN GALUR WISTAR

Sari, Meryana Tunjung (2013) UJI AKTIVITAS DIURETIK DARI MASERASI EKSTRAK ETANOL 70% DAUN PUTRI MALU (Mimosa pudica L.) TERHADAP TIKUS PUTIH JANTAN GALUR WISTAR. Skripsi thesis, Universitas Setia Budi Surakarta.

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Abstract

Putri malu (Mimosa pudica L.) leaf can be used as urine emetic (diuretic). This research aims to know the diuretic effect of ethanol 70% extract of putri malu leaf in white male mice wistar strain. Animal tests used as many as 25 tail, which are divided into 5 treatment groups those are: treatment of furosemide suspension (positive control), 1% PVP suspension (negative control), ethanol 70% extract of putri malu leaf 20 mg/200 g, 40 mg/200 g, 80 mg/200 g given orally with volume of 3 ml/200 g. Method maserasi. The diuretic effect can be seen from the data analysis results of AUC 06, AUC 6-12, AUC 12-24 and AUC 0-24 obtained from the urine volume each time of observation. Data analysis performed by parametric analysis with one way ANOVA (one way variant analysis) and Post Hoc Tests Tukey HSD with 95% significant level. The Research result obtained that ethanol 70% extract of putri malu leaf has diuretic effect. Dosage which has the most effective diuretic optimum are extract of 20 mg/200 g BB, and than 80 mg/200 g BB and the smallest 20 mg/200 g BB. Key words: extract ethanol 70%, putri malu (Mimosa pudica L.) leaf, diuretic, furosemide.

Item Type: Thesis (Skripsi)
Uncontrolled Keywords: extract ethanol 70%, putri malu (Mimosa pudica L.) leaf, diuretic, furosemide.
Subjects: R Medicine > RS Pharmacy and materia medica
Divisions: Fakultas Farmasi > Prodi S1 Farmasi
Depositing User: B Supri Yadi
Date Deposited: 20 Nov 2019 04:30
Last Modified: 20 Nov 2019 04:30
URI: http://repository.setiabudi.ac.id/id/eprint/2987

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