OPTIMASI PROPORSI ASAM STEARAT DAN TRIETANOLAMIN KRIM TABIR SURYA LAPISAN PUTIH KULIT SEMANGKA SECARA SLD DAN DIUJI AKTIVITAS ANTIOKSIDAN TERHADAP RADIKAL DPPH

Marlina, Dian (2013) OPTIMASI PROPORSI ASAM STEARAT DAN TRIETANOLAMIN KRIM TABIR SURYA LAPISAN PUTIH KULIT SEMANGKA SECARA SLD DAN DIUJI AKTIVITAS ANTIOKSIDAN TERHADAP RADIKAL DPPH. Skripsi thesis, Universitas Setia Budi Surakarta.

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01. INTISARI.pdf

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02. HALAMAN JUDUL - BAB I.pdf

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Abstract

Watermelon rind (Citrullus vulgaris, Schrad) contains antioxidants flavonoids that act as a good reducing for both of the OH radical and the superoxide. The direct use of watermelon rind is impratical, further in 2012, Hidayah made it as sunscreen cream. The purposes of this research are to obtain the optimum formula of sunscreen cream of watermelon rind on the proportion of stearic acid and triethanolamine using the simplex lattice design methods and to investigate the antioxidant activity in those pharmaucetical dosages form. The viscous watermelon rind extract was obtained by the maceration using 70% ethanol. Te sunscreen cream of watermelon rind was made in the three different formulas based on the simplex lattice design. The resulting cream was tested against the parameters of viscosity, adhesion power, and dispersive power. The optimum formula was obtained by using the Design Expert 8.0.6 software. Those results were furthermore compared with the theoretical results using T-test with the level of significance 95%. The antioxidant activity was determined by the DPPH method (1,1 diphenil-2pikrilhidrazil) and using rutin as the comparator then the IC50 values calculated by the probit method. The results show that the optimum formula of sunscreen cream of watermelon rind was obtained on the proportion of 50% stearic acid and 50% triethanolamine. Whereas the sunscreen cream of watermelon rind (Citrullus vulgaris, Schrad) has the antioxidant activity with the IC50 value of 87,579 ppm. Key words: cream, sunscreen, antioxidants, optimization, watermelon rind (Citrullus vulgaris, Schrad).

Item Type: Thesis (Skripsi)
Uncontrolled Keywords: cream, sunscreen, antioxidants, optimization, watermelon rind (Citrullus vulgaris, Schrad).
Subjects: Q Science > QD Chemistry
R Medicine > RS Pharmacy and materia medica
Divisions: Fakultas Farmasi > Prodi S1 Farmasi
Depositing User: magdalena kartika ningsih
Date Deposited: 21 Feb 2020 03:45
Last Modified: 21 Feb 2020 03:45
URI: http://repository.setiabudi.ac.id/id/eprint/2932

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