SINTESIS SENYAWA 3-(4-KLOROFENIL)-1-(4-PIRIDINIL) PROP-2-EN-1-ON MENGGUNAKAN MATERIAL AWAL p-KLOROBENZALDEHID DAN p-ASETILPIRIDIN DALAM KATALIS BASA DENGAN PELARUT ETANOL

Apriyanto, Ade Indra (2013) SINTESIS SENYAWA 3-(4-KLOROFENIL)-1-(4-PIRIDINIL) PROP-2-EN-1-ON MENGGUNAKAN MATERIAL AWAL p-KLOROBENZALDEHID DAN p-ASETILPIRIDIN DALAM KATALIS BASA DENGAN PELARUT ETANOL. Skripsi thesis, Universitas Setia Budi Surakarta.

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Abstract

Chalcone is a precursor of flavonoid’s in the system α,β-unsaturated carbonyl carbon where the third joining the two aromatic rings have several biological activities as antibacterial, as antimicrobial, anticancer, antioxidant, antiinflammatory and antimalarial. This study aims to synthesize the compound 3-(4chlorophenyl)-1-(4-pyridinyl)prop-2-en-1-on Chlaisen-Schmidt method between p-acetylpyridyn and p-chlorobenzaldehide used NaOH as catalyst in ethanol solution. The compound 3-(4-chlorophenyl)-1-(4-pyridinyl)prop-2-en-1-on with the initial material with p-acetylpyridyn and p-chlorobenzaldehide, NaOH was used as catalyst in ethanol at room temperature. Thin layer chromatography, melting point test, gas chromatography, mass spectrometry, UV spectrometer, and IR spectrometer was used as Purity Test of compounds metode The results showed that the compound 3-(4-chlorophenyl)-1- (4-pyridinyl) prop-2-en-1-on has been successfully synthesized by the chemical structures that have been estimated. Purity Test of compounds methode showed that the compound hasn’t pure, and than with structure elusidation the compound have yield 89,05%. Keywords : Synthesis of 3 - (4-chlorophenyl) -1 - (4-pyridinyl) prop-2-en-1-one, NaOH, p-chlorobenzaldehid, p-asetylpyridine

Item Type: Thesis (Skripsi)
Uncontrolled Keywords: Synthesis of 3 - (4-chlorophenyl) -1 - (4-pyridinyl) prop-2-en-1-one, NaOH, p-chlorobenzaldehid, p-asetylpyridine
Subjects: Q Science > QD Chemistry
R Medicine > RS Pharmacy and materia medica
Divisions: Fakultas Farmasi > Prodi S1 Farmasi
Depositing User: magdalena kartika ningsih
Date Deposited: 21 Feb 2020 03:34
Last Modified: 21 Feb 2020 03:34
URI: http://repository.setiabudi.ac.id/id/eprint/2794

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