EFEK DIURETIK INFUS DAUN KACANG PANJANG (Vigna sinensis (L.) Savi ex Hassk.) PADA TIKUS PUTIH JANTAN GALUR WISTAR

Untari, Sri (2015) EFEK DIURETIK INFUS DAUN KACANG PANJANG (Vigna sinensis (L.) Savi ex Hassk.) PADA TIKUS PUTIH JANTAN GALUR WISTAR. Karya Tulis Ilmiah thesis, Universitas Setia Budi Surakarta.

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Abstract

Long beans (Vigna sinensis (L.) Savi ex Hassk.) Is one of the medicinal plants. The leaves and roots are efficacious as a diuretic. The study purpose was determined the diuretics effect and determined the long bean leaf infusion dose are effective as a diuretic in male white wistar strain rats. The solvent was used for the extraction of long beans leaves is water. The study method was used infundation. The infusion of the long beans leaves were tested on male white wistar strain rats. The tested animals were divided into 5 groups each group consisted of 5 male white wistar strain rats. Group I is negative control of 0.5% CMC suspension (2.5 ml/200 g BW), group II is positive control of furosemide (0.72 mg/200 g BW), group III, IV and V are preparations of long bean leaves infusion (0,225 g/200 g BW, 0.45 g/200 g BW and 0.9 g/200 g BW). Infusion was administered orally and then observed the diuretic effects for 6 hours. The data was analyzed using 1-way ANOVA followed Post Hoc Test Tukay HSD α = 0.05). From the research result was obtained the long beans leaves infusion have a diuretic effect. The effective dose was 0.9 g/200 g BW with total AUC value of 3.94 ml.h and percentage of diuretic power is 87.61%. Keywords: Leaves of longs beans (Vigna sinensis (L.) Savi ex Hassk.), Infusion, diuretic.

Item Type: Thesis (Karya Tulis Ilmiah)
Uncontrolled Keywords: Leaves of longs beans (Vigna sinensis (L.) Savi ex Hassk.), Infusion, diuretic.
Subjects: R Medicine > RS Pharmacy and materia medica
S Agriculture > S Agriculture (General)
Divisions: Fakultas Farmasi > Prodi D3 Farmasi
Depositing User: magdalena kartika ningsih
Date Deposited: 20 Feb 2020 04:14
Last Modified: 20 Feb 2020 04:14
URI: http://repository.setiabudi.ac.id/id/eprint/2179

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