UJI AKTIVITAS FRAKSI-FRAKSI KULIT BUAH SALAK PONDOH (Salacca zalacca [Gaertner] Voss) TERHADAP KADAR ASAM URAT AYAM LEGHORN JANTAN

WIJAYA, Selvy (2016) UJI AKTIVITAS FRAKSI-FRAKSI KULIT BUAH SALAK PONDOH (Salacca zalacca [Gaertner] Voss) TERHADAP KADAR ASAM URAT AYAM LEGHORN JANTAN. Skripsi thesis, Universitas Setia Budi Surakarta.

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Abstract

Hiperuricemia is condition that increased of uric acid level in the blood serum. Pondoh salacca rind contains flavonoids and saponins which could be decreased the level of uric acid. The purpose of this research is to know the activity of fractions of pondoh salacca rind in reduce uric acid level in leghorn cock that induced liver juice. The research used 24 leghorn cock that divided randomly in 6 groups. They were normal control group, the negative control group that given CMC 0,5%, positive control group was given allopurinol, and test group that given ethanol extract of pondoh salacca rind, ethyl acetate fraction and water fraction that given 175,14 mg/1,5 kgBW; 15,80 mg/1,5 kgBW; 124,40 mg/1,5 kgBW respectively. The leghorn cock was induced by chicken liver juice in dose 5 ml/kgBW orally. The blood take was conducted in three times, the day of 0, 7 th and 14 th days in lateralis vena of leghorn cock. The uric acid levels were measured by the spectrophotometer Start Dust. Data were analyzed using the analysis of variance one way ANOVA. The result of this research was the fraction of ethyl acetate has the potential to lower uric acid levels. The ethanol extract of pondoh salacca rind 175,14 mg/1,5 kgBW was samet with positive control that given allopurinol. Keywords: the fractions, pondoh salacca rind, hiperuricemia, leghorn cock.

Item Type: Thesis (Skripsi)
Uncontrolled Keywords: the fractions, pondoh salacca rind, hiperuricemia, leghorn cock.
Subjects: R Medicine > RS Pharmacy and materia medica
Divisions: Fakultas Farmasi > Prodi S1 Farmasi
Depositing User: Tifany Nur Arfiana
Date Deposited: 01 Oct 2019 03:27
Last Modified: 01 Oct 2019 03:27
URI: http://repository.setiabudi.ac.id/id/eprint/1479

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