PENGARUH VARIASI KONSENTRASI TRIETANOLAMIN DAN ASAM STEARAT TERHADAP MUTU FISIK KRIM ANTIOKSIDAN EKSTRAK DAUN MANGGIS (Garcinia mangostana L.) DENGAN METODE FACTORIAL DESIGN

LIANA, Khoiril (2016) PENGARUH VARIASI KONSENTRASI TRIETANOLAMIN DAN ASAM STEARAT TERHADAP MUTU FISIK KRIM ANTIOKSIDAN EKSTRAK DAUN MANGGIS (Garcinia mangostana L.) DENGAN METODE FACTORIAL DESIGN. Skripsi thesis, Universitas Setia Budi Surakarta.

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Abstract

Mangosteen is one of the medicinal plants which has been proven to have antioxidant activity. Direct use of mangosteen leaf extract as antioxidant was less practical, so was to made preparations into cream dosage form. The aim of this study was to know various concentration effect of trietanolamin and stearic acid the qualityproperties of the cream preparation with factorial design, as well as to fine out the antioxidant activity of the extract and cream. Mangosteen leaves were extracted by maceration method using ethanol 70%to obtain a thick extracts. Cream was made into four formula of various concentration of stearic acid and triethanolamine based on factorial design. Cream produced is tested physical quality include viscosity, dispersive power, adhesivity, pH and antioxidant activity. Determine the effect of variation concentration of triethanolamine and stearic acid using factorial design program Design Expert version 8.0.6.1. The results showed that stearic acid increased concentration and triethanolamine affected the increased viscosity, increased adhesivity and decreased dispersive power and pH decreased. The result of antioxidant activity test extracts, the formula I, A, B and AB respectively, were 11,614; 81,618; 84,566; 82,603; 84,586 ppm. Keywords: mangosteen extract cream, factorial design, stearic acid, triethanolamine, antioxidant.

Item Type: Thesis (Skripsi)
Uncontrolled Keywords: mangosteen extract cream, factorial design, stearic acid, triethanolamine, antioxidant.
Subjects: R Medicine > RS Pharmacy and materia medica
Divisions: Fakultas Farmasi > Prodi S1 Farmasi
Depositing User: Tifany Nur Arfiana
Date Deposited: 01 Oct 2019 03:14
Last Modified: 01 Oct 2019 03:14
URI: http://repository.setiabudi.ac.id/id/eprint/1396

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