UJI AKTIVITAS ANTIJAMUR FRAKSI n-HEKSAN, ETIL ASETAT DAN AIR EKSTRAK ETANOL DAUN TANJUNG (Mimusops elengi Linn) TERHADAP Candida albicans ATCC 10231 SECARA IN VITRO

AGNANDHANY, Cininta Dea (2016) UJI AKTIVITAS ANTIJAMUR FRAKSI n-HEKSAN, ETIL ASETAT DAN AIR EKSTRAK ETANOL DAUN TANJUNG (Mimusops elengi Linn) TERHADAP Candida albicans ATCC 10231 SECARA IN VITRO. Skripsi thesis, Universitas Setia Budi Surakarta.

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Abstract

Fluor albus, thrush and candidiasis is an infection caused by the fungus Candida albicans. Tanjung leaves have the constituent compounds are flavonoids, alkaloids, saponins, triterpenoids, and tannins. This study aimed to determine the activity of the fraction of n-hexane, ethyl acetate, and water ethanol extract of cape leaf (Mimusops elengi Linn) as antifungals against Candida albicans ATCC 10231. The extraction method used in this study is the percolation method with 70% ethanol, followed by fractionation of the solvent n-hexane, ethyl acetate and water. Test antifungal activity against Candida albicans done by dilution method. The concentration of ethanol extract and fractions used 50%; 25%; 12.5%; 6.25%; 3.12%; 1.56%; 0.78%; 0.39%; 0.19%; 0.09%. Analysis of compounds made with reaction tubes and TLC. The results showed that the ethanol extract of leaves of the promontory, the fraction of n-hexane, ethyl acetate and water have antifungal activity against Candida albicans. Ethyl acetate fraction has the most effective antifungal activity against Candida albicans than the fraction of n-hexane, ethyl acetate and ethanol extracts of cape leaf. Minimum Kill Concentration (MKC) 6:25%, and MKC positive control albothyl is 0.25%. The most-active compounds in the fraction of ethyl acetate are flavonoids. Keywords: Tanjung leaves (Mimusops elengi Linn), Candida albicans ATCC 10231, antifungal

Item Type: Thesis (Skripsi)
Uncontrolled Keywords: Tanjung leaves (Mimusops elengi Linn), Candida albicans ATCC 10231, antifungal
Subjects: R Medicine > RS Pharmacy and materia medica
Divisions: Fakultas Farmasi > Prodi S1 Farmasi
Depositing User: Tifany Nur Arfiana
Date Deposited: 30 Sep 2019 02:19
Last Modified: 30 Sep 2019 02:19
URI: http://repository.setiabudi.ac.id/id/eprint/1334

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