UJI SITOTOKSIK EKSTRAK ETANOL KULIT BUAH JERUK NIPIS (Citrus aurantifolia) TERHADAP SEL KANKER PAYUDARA T47D

BERTHA, Bertha (2016) UJI SITOTOKSIK EKSTRAK ETANOL KULIT BUAH JERUK NIPIS (Citrus aurantifolia) TERHADAP SEL KANKER PAYUDARA T47D. Skripsi thesis, Universitas Setia Budi Surakarta.

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Abstract

Breast cancer is one of the most common cancer cause of death. Breast cancer not only suffered by women, but can also attack the boy. In Indonesia there are many herbs that are potentially as anticancer, one of which is the lime (Citrus aurantifolia). The leaves of the lemon has a few compounds such as flavonoids, saponins, and essential oils that have been researched can be cytotoxic cancer cells agains breast cancer T47D. Lime peel extraction is done by the method of maceration with ethanol solvent 96%. T47D cells against the citotoxicity test is performed by the method MTT assay with the concentration of 18,75; 37,5; 75; 150; 300µg/mL .Cytotoxicity test results ethanol extract of lemon peel in rind that is absorbed is converted into response percent viability of cells then proceeded to determine the linear. Extract lemon skin have IC50 of value 19.512 less than 30 µ g/mL so that potential is to be developed. Whereas the IC50 value of doksorubisin as the comparison compounds is lower than Citrus aurantifolia and lower than 100 µg/mL is 0.9 µg/mL. Keyword : lime peel, (Citrus aurantifolia), T47D cells, MTT assay, cytotoxicity

Item Type: Thesis (Skripsi)
Uncontrolled Keywords: lime peel, (Citrus aurantifolia), T47D cells, MTT assay, cytotoxicity
Subjects: R Medicine > RS Pharmacy and materia medica
Divisions: Fakultas Farmasi > Prodi S1 Farmasi
Depositing User: Tifany Nur Arfiana
Date Deposited: 30 Sep 2019 02:16
Last Modified: 30 Sep 2019 02:16
URI: http://repository.setiabudi.ac.id/id/eprint/1328

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