UJI AKTIVITAS ANTIBAKTERI SALEP EKSTRAK KULIT BATANG KESAMBI (Schleichera oleosa Merr) TERHADAP Staphylococcus aureus ATCC 25923 YANG DIINFEKSIKAN PADA KELINCI

DHEGO, Anastasia Paula (2016) UJI AKTIVITAS ANTIBAKTERI SALEP EKSTRAK KULIT BATANG KESAMBI (Schleichera oleosa Merr) TERHADAP Staphylococcus aureus ATCC 25923 YANG DIINFEKSIKAN PADA KELINCI. Skripsi thesis, Universitas Setia Budi Surakarta.

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Abstract

Kesambi (Scheichera oleosa Merr.) is a plants that contains saponins, tannins, alkaloids and triterpenoids which is suspect to have antibacterial activity. The aim of the study was to find out the antibacterial activity of kesambi bark ethanol extract ointment and the effective concentration against Staphylococcus aureus ATCC 25923 infected on the back skin of rabbits. The extraction was done by maceration using ethanol 70%. Formulas of kesambi bark extract ointment were made with hydrocarbon basic in three concentrations i.e. 6.25%, 12.5% and 25%, with gentamycin ointment as positive control. Observation of healing time was done by observing the length of healing infection of the skin on the back skin of rabbits, after administration of kesambi bark extract ointment kesambi characterized by the loss of erythema and puss. The obtained data was analyzed using Paired-samples one way ANOVA (significance p <0.05). The results showed that kesambi bark extract ointment kesambi had the effectiveness in healing Staphylococcus aureus bacterial infection and there were differences of effectiveness in each concentration. The healing effect of kesambi bark extract ointment in concentration of 25% was more than the concentration of 12.5% and 6.25%. Keywords: kesambi bark ointment, antibacterial, Staphylococcus aureus ATCC 25923.

Item Type: Thesis (Skripsi)
Uncontrolled Keywords: kesambi bark ointment, antibacterial, Staphylococcus aureus ATCC 25923.
Subjects: R Medicine > RS Pharmacy and materia medica
Divisions: Fakultas Farmasi > Prodi S1 Farmasi
Depositing User: Tifany Nur Arfiana
Date Deposited: 26 Sep 2019 07:53
Last Modified: 26 Sep 2019 07:53
URI: http://repository.setiabudi.ac.id/id/eprint/1308

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