AKTIVITAS ANTIBAKTERI FRAKSI n-HEKSANA, ETIL ASETAT, DAN AIRDARI EKSTRAK METANOL DAUN KENIKIR (Cosmos caudatus Kunth.) TERHADAP Klebsiella pneumoniae ATCC 10031

Maryono, Tri (2017) AKTIVITAS ANTIBAKTERI FRAKSI n-HEKSANA, ETIL ASETAT, DAN AIRDARI EKSTRAK METANOL DAUN KENIKIR (Cosmos caudatus Kunth.) TERHADAP Klebsiella pneumoniae ATCC 10031. Skripsi thesis, Universitas Setia Budi Surakarta.

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Abstract

Cosmos leaves (Cosmos caudatus Kunth.) contain flavonoid, saponin, volatil oil and alkaloid. The purpose of this study was to determine the activity of n-hexane fraction, ethyl acetate fraction, the fraction of water and ethanol extracts of leaves of Cosmos (Cosmos caudatus Kunth.) as an antibacterial against Klebsiella pnumoniae ATCC 10031. Cosmos leaves powder macerated withmethanol, and then fractionated using n-hexane, ethyl acetate, and water solvents.Methanol extract, n-hexane, ethyl acetate, and water fractions were tested antibacterial activity using difution method with concentrations of 50%; 25%; 12,5 and dilution method with concentrations of 50.0%; 25%; 12.5%; 6.25%; 3.125%; 1.56%; 0.78%; 0.390%; 0.195%of the bacteria Klebsiella pnumoniae ATCC 10031. The results showed that the fraction of n-hexane,ethyl acetate, water, and Cosmos leaf extract has antibacterial activity against Klebiella pneumonia the diffusion method shown that at a concentration of 50% the fraction and extract provide the inhibition that most large power resistor of each fraction n-hexane 18,5 mm,ethyl acetate 21,2 mm, water 16,3 mm and extract 15,8 mm and the method of dilution on the fraction of the most active ethy acetate fraction of the value of KBM 25% based on the above results it can be concluded that the ethyl acetate fraction at a concentration of 50% is fraction of most active. Keywords: Cosmos caudatus Kunth.,Klebsiella pneumoniae 10031,antibacterial, the fraction of n-hexane, ethylacetat fraction, the fraction of water

Item Type: Thesis (Skripsi)
Uncontrolled Keywords: Cosmos caudatus Kunth.,Klebsiella pneumoniae 10031,antibacterial, the fraction of n-hexane, ethylacetat fraction, the fraction of water
Subjects: R Medicine > RS Pharmacy and materia medica
Divisions: Fakultas Farmasi > Prodi S1 Farmasi
Depositing User: Herera Gadys USB
Date Deposited: 25 Feb 2019 03:41
Last Modified: 25 Feb 2019 03:41
URI: http://repository.setiabudi.ac.id/id/eprint/1251

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