UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL, FRAKSI n-HEKSANA, ETIL ASETAT, DAN AIR DARI DAUN BIDARA (Zizyphus mauritiana Lamk.) TERHADAP Salmonella typhi ATCC 13311

AGUSTINA, Widia (2018) UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL, FRAKSI n-HEKSANA, ETIL ASETAT, DAN AIR DARI DAUN BIDARA (Zizyphus mauritiana Lamk.) TERHADAP Salmonella typhi ATCC 13311. Skripsi thesis, Universitas Setia Budi Surakarta.

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Abstract

The bidara plant (Zizyphus mauritiana Lamk.) in traditional medicines can be used to treat a variety of ailments flu, convulsions, and malnutrition related diseases in children. Phytochemical analysis of methanolic extract of bidara leaves contains saponin, tannins, flavonoids, terpenoids, phenolic compounds. Tannins can be used antimicrobial and antioxidant. Saponin can be used anticancer, antifungal, antiinflamatory, and antibacterial. This study aims to determine of activity of the fraction of n-hexsane, ethyl acetat, water and ethanol extract of bidara leaf’s as antibacterial Salmonella typhi ATCC 13311. Bidara leaf (Zizyphus mauritiana Lamk.) was extraced by maceration method used ethanol 70%, than fractionation used n-hexsane, ethyl acetat, and water solvents. Antibacterial activity fraction and extraction was tested for diffution method and dilution methode. Diffution methode with serial concentrations of 50%; 25%; 12,5%. The most effective compounds than tested with dilution. Bacteria test using Salmonella typhi ATCC 13311. The results showed that ethanol extract, fraction of n-hexsane, ethyl acetat, and water from bidara leaf had antibacterial activity against Salmonella typhi ATCC 13311. Concentration of 50% ethyl acetat fraction had the most effective antibacterial activity with inhibitory diameter of 14 mm and Minimum Kill Concentration (MKC) of 12,5 % against Salmonella typhi ATCC 13311 bacteria. Keywords: Zizyphus mauritiana Lamk., Salmonella typhi ATCC 13311, fraction n-hexsane, fraction ethyl acetat, fraction water.

Item Type: Thesis (Skripsi)
Uncontrolled Keywords: Zizyphus mauritiana Lamk., Salmonella typhi ATCC 13311, fraction n-hexsane, fraction ethyl acetat, fraction water.
Subjects: R Medicine > RS Pharmacy and materia medica
Divisions: Fakultas Farmasi > Prodi S1 Farmasi
Depositing User: Tifany Nur Arfiana
Date Deposited: 25 Feb 2019 03:41
Last Modified: 25 Feb 2019 03:41
URI: http://repository.setiabudi.ac.id/id/eprint/1244

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