ANALISIS INTERAKSI OBAT ANTIPSIKOTIK PADA PENDERITA SKIZOFRENIA DI INSTALASI RAWAT INAP RSJD DR. RM. SOEDJARWADI KLATEN TAHUN 2016

Sari, Putri Pamungkas (2017) ANALISIS INTERAKSI OBAT ANTIPSIKOTIK PADA PENDERITA SKIZOFRENIA DI INSTALASI RAWAT INAP RSJD DR. RM. SOEDJARWADI KLATEN TAHUN 2016. Skripsi thesis, Universitas Setia Budi Surakarta.

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Abstract

Schizophrenia is categorized as a severe mental illness. The indicated symptoms are such as delusions,hallucinations and agitation. This research was done to find out the analysis drug interactions of antipsychotic that patients of schizophrenia and the mechanisms of the interaction significance level of antipsychotic drugs in the adult patients of schizophrenia at inpatients installation RSJD. DR. RM. SOEJARWADI 2016. This research which was done by using descriptive analysis is eksperimental The data was taken by retrospective technique. This research was done by analyzing the medical data records of the patient. then it was obtained 90 sample of the patients with schizophrenia who undergo hospitalization and antipsychotic medication therapy. The samples obtained in this research were the hospitalized schizophrenia patients who were selected by using inclusion criteria. There were 75 patients who met the criteria. Based on the results of the study, it was concluded that the antipsychotic drugs which widely used triheksipenidil (22,80%), haloperidol (18,60%),trifluoperazin (8,07%) and alprazolam (7,36%) Based on the mechanism result of 125 analysis interactions, found pharmacokinetic interaction at 26 cases (20,80%) and the interaction of the pharmacodynamic mechanism occurs at 99 cases (79,20%) for significance level 4, in this study were haloperidol – fluoxetin 1 sample (0,51%) and clozapin – fluoxetin 1 sample (0,51%) Keywords : drug interactions, schizophrenia, antipsychotic, mechanism drug interaction

Item Type: Thesis (Skripsi)
Uncontrolled Keywords: drug interactions, schizophrenia, antipsychotic, mechanism drug interaction
Subjects: R Medicine > RS Pharmacy and materia medica
Divisions: Fakultas Farmasi > Prodi S1 Farmasi
Depositing User: Herera Gadys USB
Date Deposited: 25 Feb 2019 03:17
Last Modified: 25 Feb 2019 03:17
URI: http://repository.setiabudi.ac.id/id/eprint/1061

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