UJI AKTIVITAS ANTI BAKTERI SEDIAAN GEL Hand Sanitizer EKSTRAK ETANOL DAUN PACAR KUKU (Lawsonia inermis L.) TERHADAP BAKTERI Staphylococcus aureus ATCC 25923

Anggraini, Ovi (2018) UJI AKTIVITAS ANTI BAKTERI SEDIAAN GEL Hand Sanitizer EKSTRAK ETANOL DAUN PACAR KUKU (Lawsonia inermis L.) TERHADAP BAKTERI Staphylococcus aureus ATCC 25923. Skripsi thesis, Universitas Setia Budi Surakarta.

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Abstract

Pacar Kuku leaves contain much bioactive compounds substances which is efficacious as medicine. One of the efficacy of the pacar Kuku leaves is that it is an antimicrobial substance derived from the content of alkaloids, flavonoids, saponins, and quinons. The purpose of this study was to find out the formulation of the hand gel form of ethanol extract of pacar kuku leaves (Lawsonia inermis L.) as antibacterial with various concentration of ethanol extract of pacar kuku leaves that can work well against Staphylococcus aureus bacteria. The extraction method used was a maceration method using 70% ethanol solvent. Hand-cleaning gel of pacar kuku leaves ethanol extract made 4 formulations. Formula 1 contains 0,25, formula2 contains 0,50, formula 3 contains 0,75, and formula 4 contains 1 gram ethanol extract of pacar kuku leaves. The negative control used hand sanitizer gel without ethanol extract of pacar kuku leaves and the positive control useddettol hand sanitizer. The testsused include organoleptic test, pH test, spreading test, sticky test, homogeneity test, viscosity test, gel stability test, and antibacterial activity test. Data Analysis of anti-bacterial inhibitory and data analysis of hand gel formulations used one-way anova. The results shows that the best formulation is the formula 2 because it produced a light brown color from organoleptistest that matches the good visual criteria, that is a clear and attractive gel. In addition, it has the adhesive and spreading power that almost the same with positive control and has a resistor of 14 mm and formula 4 as a larger inhibitory of 16,1 mm. Keywords: Hand sanitizer gel formulations, pacar kuku leaves, Staphylococcus aureus bacteria, carbopol 940

Item Type: Thesis (Skripsi)
Uncontrolled Keywords: Hand sanitizer gel formulations, pacar kuku leaves, Staphylococcus aureus bacteria, carbopol 940
Subjects: R Medicine > RS Pharmacy and materia medica
Divisions: Fakultas Farmasi > Prodi S1 Farmasi
Depositing User: Tifany Nur Arfiana
Date Deposited: 25 Feb 2019 03:10
Last Modified: 25 Feb 2019 03:10
URI: http://repository.setiabudi.ac.id/id/eprint/1032

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